Former President Donald Trump selected Florida Sheriff Chad Chronister to head the U.S. Drug Enforcement Administration (DEA), emphasizing border security and combating the fentanyl crisis as key priorities. Trump praised Chronister's extensive 32-year career with the Hillsborough County Sheriff's Office, highlighting his numerous accolades and commitment to public safety. He also noted Chronister's leadership roles in regional security and anti-human trafficking initiatives.

Trump underscored that Chronister would collaborate with Attorney General nominee Pam Bondi to address border security, stem the flow of fentanyl and other illicit drugs, and ultimately save lives. He extended congratulations to Chronister, his wife Nikki, and their two sons. Chronister expressed his gratitude for the nomination, describing it as "the honor of a lifetime" and conveying his humility at the opportunity to serve the nation.

Chronister's appointment to the Hillsborough County Sheriff's Office in 2017 by then-Governor Rick Scott was followed by two successful re-election campaigns. This nomination coincided with Trump's announcement of Kash Patel as his pick to replace Christopher Wray as FBI director.